Critical Care Research Lab

Publications

Welcome to the Critical Care Research Lab’s publications page. Here you’ll find our peer-reviewed journal articles, conference presentations, and other research outputs, including software and datasets. Our work focuses on the microvascular physiology of sepsis and critical illness, with an emphasis on developing innovative monitoring tools and translational models to improve patient care.

We are committed to advancing knowledge and open science. For questions about our research or collaboration opportunities, please reach out through our faculty contact page.

All Publications

Below is a chronological list of all lab publications.

2025

Development of a standardized single session cardiopulmonary exercise test for combined assessment of peak oxygen uptake and on off kinetics
Development of a standardized single‐session cardiopulmonary exercise test for combined assessment of peak oxygen uptake and on/off‐kinetics
Jefferson L. Santana, Till Enzner, Britney Blunderfield, Asher A. Mendelson, Rodrigo Villar
Experimental Physiology  ·  20 Mar 2025  ·  doi:10.1113/EP092337

2024

Microvascular Autoregulation in Skeletal Muscle Using Near-Infrared Spectroscopy and Derivation of Optimal Mean Arterial Pressure in the ICU: Pilot Study and Comparison With Cerebral Near-Infrared Spectroscopy
Microvascular Autoregulation in Skeletal Muscle Using Near-Infrared Spectroscopy and Derivation of Optimal Mean Arterial Pressure in the ICU: Pilot Study and Comparison With Cerebral Near-Infrared Spectroscopy
Amirali Mirsajadi, Dustin Erickson, Soumya Alias, Logan Froese, Amanjyot Singh Sainbhi, …, Isuru Herath, Maggie Wilson, Ryan Zarychanski, Frederick A. Zeiler, Asher A. Mendelson
Critical Care Explorations  ·  21 Jun 2024  ·  doi:10.1097/CCE.0000000000001111

2023

The role of the microcirculation and integrative cardiovascular physiology in the pathogenesis of ICU-acquired weakness
The role of the microcirculation and integrative cardiovascular physiology in the pathogenesis of ICU-acquired weakness
Asher A. Mendelson, Dustin Erickson, Rodrigo Villar
Frontiers in Physiology  ·  10 May 2023  ·  doi:10.3389/fphys.2023.1170429

2022

Capillary module haemodynamics and mechanisms of blood flow regulation in skeletal muscle capillary networks: Experimental and computational analysis
Capillary module haemodynamics and mechanisms of blood flow regulation in skeletal muscle capillary networks: Experimental and computational analysis
Asher A. Mendelson, Edward Ho, Shayla Scott, Raashi Vijay, Timothy Hunter, Stephanie Milkovich, Christopher G. Ellis, Daniel Goldman
The Journal of Physiology  ·  22 Feb 2022  ·  doi:10.1113/JP282342

2020

Dynamic tracking of microvascular hemoglobin content for continuous perfusion monitoring in the intensive care unit: pilot feasibility study
Dynamic tracking of microvascular hemoglobin content for continuous perfusion monitoring in the intensive care unit: pilot feasibility study
Asher A. Mendelson, Ajay Rajaram, Daniel Bainbridge, Keith St. Lawrence, Tracey Bentall, Michael Sharpe, Mamadou Diop, Christopher G. Ellis
Journal of Clinical Monitoring and Computing  ·  26 Oct 2020  ·  doi:10.1007/s10877-020-00611-x